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2-NBDG

Cat. No. 6065 1 Citation Submit a Review Datasheet / COA / SDS
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Description: Fluorescent glucose uptake indicator
Chemical Name: 2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
Purity: ≥97% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (1)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for 2-NBDG

2-NBDG is a fluorescent glucose analog for visualizing glucose uptake into living cells.

Optical Data for 2-NBDG

2-NBDG Dye Spectra
Emission Color Green
λabs 467 nm
λem 542 nm
Application Flow Cytometry, Confocal Microscopy

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Technical Data for 2-NBDG

M. Wt 342.26
Formula C12H14N4O8
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 186689-07-6
PubChem ID 11859095
InChI Key GVEBOQDOPLERMC-BGCUHRRXSA-N
Smiles OC1[C@H](NC(C2=NON=C32)=CC=C3[N+]([O-])=O)[C@@H](O)[C@H](O)[C@@H](CO)O1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 2-NBDG

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 34.23 100

Preparing Stock Solutions for 2-NBDG

The following data is based on the product molecular weight 342.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.92 mL 14.61 mL 29.22 mL
5 mM 0.58 mL 2.92 mL 5.84 mL
10 mM 0.29 mL 1.46 mL 2.92 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

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Product Datasheets for 2-NBDG

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References for 2-NBDG

References are publications that support the biological activity of the product.

Yamada et al (2007) A real-time method of imaging glucose uptake in single, living mammalian cells. Nat.Protoc. 2 753 PMID: 17406637

If you know of a relevant reference for 2-NBDG, please let us know.

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Keywords: 2-NBDG, 2-NBDG supplier, fluorescent, indicator, glucose, uptake, Fluorescent, Cell, Indicators, and, Sensors, Transporter, Probes, Glucose, Transporters, 6065, Tocris Bioscience

1 Citation for 2-NBDG

Citations are publications that use Tocris products. Selected citations for 2-NBDG include:

Konstantinos et al (2020) Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage. Nat Commun 11 42 PMID: 31896748

Do you know of a great paper that uses 2-NBDG from Tocris? Please let us know.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

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