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Submit ReviewBombesin
Description: Involved in gastrointestinal tract function
Purity: ≥95% (HPLC)
Biological Activity for Bombesin
Bombesin is a neuropeptide with many biological effects including hormone release, stimulation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion.
Technical Data for Bombesin
| M. Wt | 1619 |
| Formula | C71H110N24O18S |
| Sequence |
XQRLGNQWAVGHLM (Modifications: X-1 = Glp, Met-13 = C-terminal amide) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 31362-50-2 |
| PubChem ID | 16133800 |
| InChI Key | QXZBMSIDSOZZHK-DOPDSADYSA-N |
| Smiles | [H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Bombesin
References for Bombesin
References are publications that support the biological activity of the product.
Battey and Wada (1991) Two distinct subtypes for mammalian bombesin-like peptides. TiNS 14 524 PMID: 1726343
McCoy and Avery (1990) Bombesin: potential integrative peptide for feeding and satiety. Peptides 11 595 PMID: 2199952
Tache et al (1988) Central nervous system action of bombesin to influence gastric secretion and ulceration. Ann.N.Y.Acad.Sci. 547 183 PMID: 3071217
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Keywords: Bombesin, Bombesin supplier, Involved, gastrointestinal, tract, function, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, agonists, 1149, Tocris Bioscience
3 Citations for Bombesin
Citations are publications that use Tocris products. Selected citations for Bombesin include:
Shimizu et al (2017) Brain serotoninergic nervous system is involved in bombesin-induced frequent urination through brain 5-HT7 receptors in rats. Br J Pharmacol 174 3072 PMID: 28675470
Blais et al (2016) Gastrin-releasing peptide receptor mediates the excitation of preoptic GABAergic neurons by bombesin Neuroscience Letters 633 262 PMID: 27693662
Solorzano et al (2015) Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns. J Neurosci 35 648 PMID: 25589759
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.