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Submit ReviewC14TKL-1
Description: Endogenous NK1 agonist
Alternative Names: Chromosome 14 tachykinin-like peptide 1
Biological Activity for C14TKL-1
C14TKL-1 is an endogenous human tachykinin-like peptide and potent agonist for NK1 receptors (EC50 = 1 nM).
Technical Data for C14TKL-1
| M. Wt | 1406.7 |
| Formula | C63H98N20O13S2 |
| Sequence |
RHRTPMFYGLM (Modifications: Met-11 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| PubChem ID | 90488729 |
| InChI Key | MMNLXHSWHPGRFE-MRQSSJIPSA-N |
| Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for C14TKL-1
Safety Datasheet is currently unavailable on-line.
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References for C14TKL-1
References are publications that support the biological activity of the product.
Jiang et al (2003) PepPat, a pattern-based oligopeptide homology search method and the identification of a novel tachykinin-like peptide. Mamm.Genome 14 341 PMID: 12856286
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Keywords: C14TKL-1, C14TKL-1 supplier, Endogenous, NK1, agonists, Tachykinin, Receptors, Neurokinin, Chromosome14, tachykinin-like, peptide1, Chromosome, 14, peptide, 1, Receptor, 1939, Tocris Bioscience
Citations for C14TKL-1
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Currently there are no citations for C14TKL-1.
Reviews for C14TKL-1
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.