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Submit ReviewDPC AJ1951 is a potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).
M. Wt | 1666.98 |
Formula | C76H127N23O19 |
Sequence |
XVXEIQLXHQRAKY (Modifications: X-1, X-3 = Aib, X-8 = Nle, Tyr-14 = C-terminal amide) |
Storage | Store at -20°C |
CAS Number | 943519-33-3 |
PubChem ID | 44584922 |
InChI Key | PNJXWIJKATVXEY-FAQCDESUSA-N |
Smiles | [H]N([C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O)C(=O)C(C)(C)NC(=O)[C@@H](N([H])C(=O)C(C)(C)N)C(C)C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Carter et al (2007) Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe. Proc.Natl.Acad.Sci.U.S.A. 104 6846 PMID: 17428923
Keywords: DPC AJ1951, DPC AJ1951 supplier, DPCAJ1951, potent, 14, amino, acid, peptide, agonists, PTH, receptors, Parathyroid, Hormone, Receptors, 5487, Tocris Bioscience
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