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Submit ReviewDynorphin A
Description: Endogenous κ agonist
Purity: ≥95% (HPLC)
Biological Activity for Dynorphin A
Dynorphin A is a endogenous kappa receptor agonist.
Technical Data for Dynorphin A
| M. Wt | 2147.51 |
| Formula | C99H155N31O23 |
| Sequence | YGGFLRRIRPKLKWDNQ |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 80448-90-4 |
| PubChem ID | 16133805 |
| InChI Key | JMNJYGMAUMANNW-FIXZTSJVSA-N |
| Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Dynorphin A
| Solubility | Soluble to 0.80 mg/ml in water |
Product Datasheets for Dynorphin A
References for Dynorphin A
References are publications that support the biological activity of the product.
Dhawan et al (1996) International union of pharmacology XII. Classification of opioid receptors. Pharmacol.Rev. 48 567 PMID: 8981566
Tan-No et al (2008) Cysteine protease inhibitors suppress the development of tolerance to mor. antinociception. Neuropeptides 42 239 PMID: 18440066
If you know of a relevant reference for Dynorphin A, please let us know.
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Keywords: Dynorphin A, Dynorphin A supplier, Endogenous, κ-opioid, kappa-opioid, agonists, KOP, Receptors, OP2, DynorphinA, Kappa, Opioid, 3195, Tocris Bioscience
1 Citation for Dynorphin A
Citations are publications that use Tocris products. Selected citations for Dynorphin A include:
Pina et al (2020) The kappa opioid receptor modulates GABA neuron excitability and synaptic transmission in midbrain-projections from the insular cortex. Neuropharmacology 165 107831 PMID: 31870854
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