Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewDynorphin B
Discontinued Product
3196 has been discontinued.
Description: Endogenous κ agonist
Purity: ≥95% (HPLC)
Biological Activity for Dynorphin B
Dynorphin B is an opioid peptide that is the preferred endogenous agonist for the kappa opioid receptor. Displays moderate selectivity for κ1b.
Technical Data for Dynorphin B
| M. Wt | 1570.85 |
| Formula | C74H115N21O17 |
| Sequence | YGGFLRRQFKVVT |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 83335-41-5 |
| PubChem ID | 25075991 |
| InChI Key | AGTSSZRZBSNTGQ-ITZCFHCWSA-N |
| Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Dynorphin B
References for Dynorphin B
References are publications that support the biological activity of the product.
Dhawan et al (1996) International union of pharmacology. XII. Classification of opioid receptors. Pharmacol.Rev. 48 567 PMID: 8981566
Pasternak et al (1999) Antisense mapping KOR-1: evidence for multiple kappa analgesic mechanisms. Brain Res. 826 289 PMID: 10224306
Tan-No et al (2008) Cysteine protease inhibitors suppress the development of tolerance to mor. antinociception. Neuropeptides 42 239 PMID: 18440066
View Related Products by Target
View Related Products by Product Action
Keywords: Dynorphin B, Dynorphin B supplier, Endogenous, κ-opioid, kappa-opioid, agonists, KOP, Receptors, OP2, DynorphinB, Kappa, Opioid, 3196, Tocris Bioscience
1 Citation for Dynorphin B
Citations are publications that use Tocris products. Selected citations for Dynorphin B include:
Pedersen et al (2021) A novel luminescence-based-β-arrestin recruitment assay for unmodified receptors. J Biol Chem PMID: 33684444
Reviews for Dynorphin B
There are currently no reviews for this product. Be the first to review Dynorphin B and earn rewards!
Have you used Dynorphin B?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.