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Submit Reviewent-LP 99
Description: Negative Control for LP 99
Chemical Name: N-[(2S,3R)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
Purity: ≥98% (HPLC)
Biological Activity for ent-LP 99
ent-LP 99 is a negative Control for LP 99 (Cat.No. 5496).
Licensing Information
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the ent-LP 99 probe summary on the SGC website.
Compound Libraries for ent-LP 99
ent-LP 99 is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Epigenetics Library. Find out more about compound libraries available from Tocris.
Technical Data for ent-LP 99
| M. Wt | 516.05 |
| Formula | C26H30ClN3O4S |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1808948-28-8 |
| Smiles | CC(C(C=C1)=C(N2C)C=C1N3[C@@H](C4=CC=C(Cl)C=C4)[C@H](NS(=O)(CC(C)C)=O)CCC3=O)=CC2=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for ent-LP 99
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 51.6 | 100 | |
| ethanol | 51.6 | 100 |
Preparing Stock Solutions for ent-LP 99
The following data is based on the product molecular weight 516.05. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.94 mL | 9.69 mL | 19.38 mL |
| 5 mM | 0.39 mL | 1.94 mL | 3.88 mL |
| 10 mM | 0.19 mL | 0.97 mL | 1.94 mL |
| 50 mM | 0.04 mL | 0.19 mL | 0.39 mL |
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Product Datasheets for ent-LP 99
References for ent-LP 99
References are publications that support the biological activity of the product.
Clark et al (2015) LP99: discovery and synthesis of the first selective BRD7/9 bromodomain inhibitor. Angew.Chem.Int.Ed.Engl. 54 6217 PMID: 25864491
If you know of a relevant reference for ent-LP 99, please let us know.
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Citations for ent-LP 99
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