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Submit ReviewFFN 511
Description: Fluorescent substrate for VMAT2
Chemical Name: 9-(2-Aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]-benzopyrano[6,7,8-ij]quinolizin-11-one
Purity: ≥99% (HPLC)
Biological Activity for FFN 511
FFN 511 is a fluorescent false neurotransmitter (FFN). Targets neuronal vesicular monoamine transporter (VMAT) 2; inhibits serotonin binding to VMAT2 (IC50 = 1 μM). Excitation and emission maxima are 406 and 501 nm in pH 7 buffer, respectively.
Licensing Information
Sold with the permission of Columbia University
Technical Data for FFN 511
| M. Wt | 284.35 |
| Formula | C17H20N2O2 |
| Storage | Store at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 1004548-96-2 |
| PubChem ID | 23725121 |
| InChI Key | SKTIZSRPCXRDHX-UHFFFAOYSA-N |
| Smiles | NCCC(C1=C(O4)C3=C2C(CCCN2CCC3)=C1)=CC4=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for FFN 511
References for FFN 511
References are publications that support the biological activity of the product.
Gubernator et al (2009) Fluorescent false neurotransmitters visualize DA release from individual presynaptic terminals. Science 324 1441 PMID: 19423778
Zhang et al (2009) DA release at individual presynaptic terminals visualized with FFNs. J.Vis.Exp. 30 PMID: 19721412
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Citations for FFN 511
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Fluorescent Dyes and Probes Research Product GuideUpdated
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