Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewHFI 142
Description: Insulin-regulated aminopeptidase (IRAP) inhibitor
Chemical Name: Ethyl 2-amino-7-hydroxy-4-(3-pyridinyl)-4H-1-benzopyran-3-carboxylate
Purity: ≥98% (HPLC)
Biological Activity for HFI 142
Insulin-regulated aminopeptidase (IRAP) inhibitor (Ki = 2.01 μM). Improves memory in control and memory-deficient mice models.
Technical Data for HFI 142
| M. Wt | 312.32 |
| Formula | C17H16N2O4 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 332164-34-8 |
| PubChem ID | 655457 |
| InChI Key | JOPNHSIHFSZJMB-UHFFFAOYSA-N |
| Smiles | OC1=CC(OC(N)=C(C(OCC)=O)C2C3=CN=CC=C3)=C2C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for HFI 142
References for HFI 142
References are publications that support the biological activity of the product.
Albiston et al (2010) Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of Ins-regulated aminopeptidase. Mol.Pharmacol. 78 600 PMID: 20628006
View Related Products by Target
View Related Products by Product Action
Keywords: HFI 142, HFI 142 supplier, HFI, 142, inhibitors, inhibits, insulin-regulated, aminopeptidases, IRAPs, memory, Aminopeptidases, 5627, Tocris Bioscience
Citations for HFI 142
Citations are publications that use Tocris products.
Currently there are no citations for HFI 142.
Reviews for HFI 142
There are currently no reviews for this product. Be the first to review HFI 142 and earn rewards!
Have you used HFI 142?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image