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Submit Review5519 has been discontinued.
(-)-Pentazocine is a κ-opioid agonist. Displays antinociceptive in vivo.
M. Wt | 285.42 |
Formula | C19H27NO |
Storage | Store at -20°C |
Purity | ≥98% (HPLC) |
CAS Number | 7488-49-5 |
PubChem ID | 12259682 |
InChI Key | VOKSWYLNZZRQPF-KYNGSXCRSA-N |
Smiles | OC1=CC=C2C([C@](CC3)(C)[C@@H](C)[C@H](N3C/C=C(C)/C)C2)=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Mori et al (2015) Effects of (+)-pentazocine on the antinociceptive effects of (-)-pentazocine in mice. Synapse 69 166 PMID: 25559075
Keywords: (-)-Pentazocine, (-)-Pentazocine supplier, κ, opioid, agonists, agonism, antinociceptive, antinociception, analgesics, Kappa, Opioid, Receptors, 5519, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.