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Mpro 13b-H

Cat. No. 7853 Submit a Review Datasheet / COA / SDS
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Description: Negative control for Mpro 13b-K (Cat. No. 7228)
Chemical Name: tert-Butyl (1-((R)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate
Purity: ≥97% (HPLC)
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Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for Mpro 13b-H

Mpro 13b-H is a negative control for the coronavirus Mpro inhibitor, Mpro 13b-K (Cat. No. 7228).

Licensing Information

Sold under license from the University of Luebeck

Technical Data for Mpro 13b-H

M. Wt 593.68
Formula C31H39N5O7
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 3031351-76-2
InChI Key NLVRHQFXQFSBQK-OEMFJLHTSA-N
Smiles CC(C)(OC(NC1=CC=CN(C1=O)[C@@H](C(N[C@H](C(C(NCC2=CC=CC=C2)=O)=O)C[C@@H]3CCNC3=O)=O)CC4CC4)=O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Mpro 13b-H

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 11.87 20

Preparing Stock Solutions for Mpro 13b-H

The following data is based on the product molecular weight 593.68. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 8.42 mL 42.11 mL 84.22 mL
1 mM 1.68 mL 8.42 mL 16.84 mL
2 mM 0.84 mL 4.21 mL 8.42 mL
10 mM 0.17 mL 0.84 mL 1.68 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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References for Mpro 13b-H

References are publications that support the biological activity of the product.

Cooper et al (2022) Diastereomeric resolution yields highly potent inhibitor of SARS-CoV-2 main protease. J.Med.Chem. 68 13328 PMID: 36179320

If you know of a relevant reference for Mpro 13b-H, please let us know.

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Citations for Mpro 13b-H

Citations are publications that use Tocris products.

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