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Submit ReviewPeptide YY (3-36) human
Description: NPY Y2 receptor agonist
Purity: ≥95% (HPLC)
Biological Activity for Peptide YY (3-36) human
Peptide YY (3-36) human is a NPY Y2 receptor agonist. Peripheral administration inhibits food intake in mice. This effect is greater when Peptide YY (3-36) is administered in combination with GLP-1 (7-36) (Cat.No. 2082).
Technical Data for Peptide YY (3-36) human
| M. Wt | 4049.51 |
| Formula | C180H279N53O54 |
| Sequence |
IKPEAPGEDASPEELNRYYASLRHYLNLVTRQRY (Modifications: Tyr-34 = C-terminal amide) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 123583-37-9 |
| PubChem ID | 71581482 |
| InChI Key | AUHJXHCVECGTKR-RIBGVNDISA-N |
| Smiles | [H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Peptide YY (3-36) human
References for Peptide YY (3-36) human
References are publications that support the biological activity of the product.
Batterham et al (2002) Gut hormone PYY(3-36) physiologically inhibits food intake. Nature 418 650 PMID: 12167864
Neary et al (2005) Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively Endocrinology. 146 5120 PMID: 16150917
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Keywords: Peptide YY (3-36) human, Peptide YY (3-36) human supplier, Peptide, YY, human, neuropeptide, Y2, NPY, receptor, PYY, agonists, agonism, Receptors, 6288, Tocris Bioscience
Citations for Peptide YY (3-36) human
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.