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Submit ReviewPSB 069
Description: Non-selective NTPDase inhibitor
Chemical Name: 1-Amino-4-(4-chlorophenyl)aminoanthraquinone-2-sulfonic acid sodium salt
Purity: ≥98% (HPLC)
Biological Activity for PSB 069
PSB 069 is a non-selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor. Reported to inhibit rat NTPDases 1, 2 and 3 with similar potencies.
Technical Data for PSB 069
| M. Wt | 450.83 |
| Formula | C20H12N2O5ClSNa |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 78510-31-3 |
| PubChem ID | 24868311 |
| InChI Key | KINIBOSGQKLOIT-UHFFFAOYSA-M |
| Smiles | [Na+].NC1=C2C(=O)C3=CC=CC=C3C(=O)C2=C(NC2=CC=C(Cl)C=C2)C=C1S([O-])(=O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for PSB 069
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 45.08 | 100 |
Preparing Stock Solutions for PSB 069
The following data is based on the product molecular weight 450.83. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.22 mL | 11.09 mL | 22.18 mL |
| 5 mM | 0.44 mL | 2.22 mL | 4.44 mL |
| 10 mM | 0.22 mL | 1.11 mL | 2.22 mL |
| 50 mM | 0.04 mL | 0.22 mL | 0.44 mL |
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Product Datasheets for PSB 069
References for PSB 069
References are publications that support the biological activity of the product.
Baqi et al (2009) Structure activity relationships of antraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases(E-NTPDases). Purinerg.Sig. 5 91
If you know of a relevant reference for PSB 069, please let us know.
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Keywords: PSB 069, PSB 069 supplier, Non-Selective, NTPDase, inhibitors, inhibits, P-Type, ATPase, V-Type, E-Type, F-Type, ATPases, GTPases, PSB069, 2573, Tocris Bioscience
1 Citation for PSB 069
Citations are publications that use Tocris products. Selected citations for PSB 069 include:
Ibáñez et al (2012) A high throughput scintillation proximity imaging assay for protein methyltransferases. Comb Chem High Throughput Screen 15 359 PMID: 22256970
Do you know of a great paper that uses PSB 069 from Tocris? Please let us know.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.