Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewSBP1
Description: ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain
Purity: ≥95% (HPLC)
Biological Activity for SBP1
SBP1 is a human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication).
Please note - unpublished, in-house data suggests approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.
Technical Data for SBP1
| M. Wt | 2802.05 |
| Formula | C127H185N31O41 |
| Sequence |
IEEQAKTFLDKFNHEAEDLFYQS (Modifications: Ser-23 = C-terminal amide) |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| InChI Key | VTVUOJBJFPPIBF-SDBILGLNSA-N |
| Smiles | O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(N)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for SBP1
References for SBP1
References are publications that support the biological activity of the product.
Zhang et al (2020) Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD. BioRxiv - Paper not yet peer reviewed
View Related Products by Target
Keywords: SBP1, SBP1 supplier, spike, binding, protein, SARS-CoV-2, receptor, domain, RBD, COVID-19, severe, acute, respiratory, syndrome, ACE2, peptide, fluorescent, FITC, 7233, Tocris Bioscience
Citations for SBP1
Citations are publications that use Tocris products.
Currently there are no citations for SBP1.
Reviews for SBP1
There are currently no reviews for this product. Be the first to review SBP1 and earn rewards!
Have you used SBP1?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image