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SGC 6870N

Cat. No. 7184 Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Description: Negative control for SGC 6870 (Cat. No. 7182)
Chemical Name: (S)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (1)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for SGC 6870N

SGC 6870N is a negative control for SGC 6870 (Cat. No. 7182). SGC 6870N is the (S)-enantiomer, which is inactive on PRMT6.

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC 6870N probe summary on the SGC website.

Compound Libraries for SGC 6870N

SGC 6870N is also offered as part of the Tocriscreen Epigenetics Library. Find out more about compound libraries available from Tocris.

Technical Data for SGC 6870N

M. Wt 469.4
Formula C23H21BrN2O2S
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 2561471-15-4
PubChem ID 155970208
InChI Key NIPTUMFVYBXSMZ-QFIPXVFZSA-N
Smiles CC1=CC=C2C([C@H](C3=CC(C)=CC(C)=C3)N(C(C4=CC=C(Br)S4)=O)CC(N2)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for SGC 6870N

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 46.94 100
ethanol 46.94 100

Preparing Stock Solutions for SGC 6870N

The following data is based on the product molecular weight 469.4. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL
10 mM 0.21 mL 1.07 mL 2.13 mL
50 mM 0.04 mL 0.21 mL 0.43 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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References for SGC 6870N

References are publications that support the biological activity of the product.

If you know of a relevant reference for SGC 6870N, please let us know.

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Keywords: SGC 6870N, SGC 6870N supplier, SGC6870N, negative, controls, PRMT6, inhibitors, SGC, Protein, Arginine, Methyltransferases, 7184, Tocris Bioscience

Citations for SGC 6870N

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Epigenetics Scientific Review

Epigenetics Scientific Review

Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.