Cat. No. |
Product Name / Activity |
7283 |
Apilimod dimesylate |
| Inhibits production of IL-12 and IL-23; potent and selective PIKfyve inhibitor |
6438 |
BRD 6989 |
| IL-10 production enhancer; Cdk8 inhibitor |
4316 |
Bropirimine |
| Immunomodulatory and antitumor compound |
4204 |
BTZO 1 |
| MIF binder |
4400 |
(±)-CPSI 1306 |
| Reported macrophage migration inhibitory factor (MIF) inhibitor |
5479 |
CRID3 sodium salt |
| Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production |
2471 |
ER 27319 maleate |
| Inhibits TNF-α production |
1798 |
Gabexate mesylate |
| Inhibits TNF-α production. Also antithrombotic agent |
3270 |
GIT 27 |
| Immunomodulator; reduces production of pro-inflammatory cytokines |
7866 |
IDR 1002 |
| Innate Defence Regulator Peptide |
5126 |
iMDK |
| Suppressor of MDK expression; inhibits PI 3-K signaling |
3429 |
4-IPP |
| Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate |
5185 |
JTE 607 dihydrochloride |
| Cytokine release inhibitor; anti-inflammatory |
6305 |
Lenalidomide |
| TNF-α inhibitor; inhibits angiogenesis; also cereblon binder |
1093 |
Pirfenidone |
| Antifibrotic agent; regulates cytokine levels in vivo |
6302 |
Pomalidomide |
| TNF-α inhibitor; also cereblon ubiquitination inhibitor and antiangiogenic |
0652 |
Thalidomide |
| TNF-α synthesis inhibitor; also binds cereblon |
7937 |
Trofinetide |
| Suppressor of IL-1β, TNF-α, IFN-γ and E-selectin expression; IGF-1 synthetic analog |