Glucagon Receptors
The glucagon receptor is a member of the glucagon receptor family that also includes GLP-1, GLP-2, secretin, GHRH and GIP receptors. The glucagon receptor regulates blood glucose levels and is predominantly expressed in the pancreas, liver and kidneys.
Glucagon Receptor Agonists |
|
---|---|
Cat. No. | 产品名称/活性 |
6927 | Glucagon (Human, Porcine) |
Endogenous glucagon receptor agonist | |
Glucagon Receptor Antagonists |
|
Cat. No. | 产品名称/活性 |
2216 | des-His1-[Glu9]-Glucagon (1-29) amide |
Glucagon receptor antagonist | |
2311 | L-168,049 |
Potent, orally active human glucagon receptor antagonist | |
Glucagon Receptor Modulators |
|
Cat. No. | 产品名称/活性 |
6807 | NNC 0640 |
Negative allosteric modulator of glucagon and GLP-1 receptors |
The glucagon receptor is a member of the glucagon receptor family that also includes GLP-1, GLP-2, secretin, GHRH and GIP receptors. The glucagon receptor regulates blood glucose levels via control of hepatic glycogenolysis and gluconeogenesis, and via regulation of insulin release from the β-cells of pancreatic islets.
The glucagon receptor is predominantly expressed in the pancreas, liver and kidneys, but is also found to a lesser extent in the heart, adipose tissue, spleen, thymus and adrenal glands. The human glucagon receptor gene is localized on chromosome 17q25.
External sources of pharmacological information for Glucagon Receptors :
Literature for Glucagon Receptors
Tocris offers the following scientific literature for Glucagon Receptors to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.