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说明： Metabolic chemical reporter for studying glycosylation and glycoproteins
化学名： 2-Deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-D-glucopyranose-1,3,4,6-tetraacetate
纯度： ≥95% (HPLC)
生物活性 for Ac4GlcNAlk
Ac4GlcNAlk is a metabolic chemical reporter (MCR) for studying cell surface glycosylation. It is used for identification of O-GlcNAc modified proteins. In cells expressing the engineered pyrophosphorylase, mut-AGX1, Ac4GlcNAlk is efficiently converted into UDP-GlcNAlk which is incorporated into GlcNAlk-containing glycoproteins.
技术数据 for Ac4GlcNAlk
| 分子量 | 427.41 |
| 公式 | C19H25NO10 |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 1361993-37-4 |
| PubChem ID | 101797984 |
| InChI Key | PODQGPKRSTUNAT-ULAPBGCESA-N |
| Smiles | CC(OC[C@H]1OC([C@@H]([C@H]([C@@H]1OC(C)=O)OC(C)=O)NC(CCC#C)=O)OC(C)=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Ac4GlcNAlk
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| DMSO | 42.74 | 100 |
制备储备液 for Ac4GlcNAlk
以下数据基于产品分子量 427.41。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.34 mL | 11.7 mL | 23.4 mL |
| 5 mM | 0.47 mL | 2.34 mL | 4.68 mL |
| 10 mM | 0.23 mL | 1.17 mL | 2.34 mL |
| 50 mM | 0.05 mL | 0.23 mL | 0.47 mL |
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产品说明书 for Ac4GlcNAlk
参考文献 for Ac4GlcNAlk
参考文献是支持产品生物活性的出版物。
Cioce et al (2021) Optimization of metabolic oligosaccharide engineering with Ac4GalNAlk and Ac4GlcNAlk by an engineered pyrophosphorylase. ACS Chem.Biol. 16 1961 PMID: 33835779
If you know of a relevant reference for Ac4GlcNAlk, please let us know.
关键词: Ac4GlcNAlk, Ac4GlcNAlk supplier, bio-orthogonal, glycosylation, glycoproteins, probes, labeling, labelling, metabolic, chemical, reporter, MCR, O-GlcNAc, Glycobiology, Probes, Post-translational, Modifications, 7750, Tocris Bioscience
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