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Submit ReviewAmyloid β-peptide (25-35) (human) is a fragment of human amyloid β-peptide, functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease.
分子量 | 1060.27 |
公式 | C45H81N13O14S |
序列 | GSNKGAIIGLM |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 131602-53-4 |
PubChem ID | 10843733 |
InChI Key | WIHBNMPFWRHGDF-SLVFWPMISA-N |
Smiles | [H]NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性 | Soluble to 0.50 mg/ml in water |
参考文献是支持产品生物活性的出版物。
Rush et al (1992) Intracerebral β-amyloid(25-35) produces tissue damage: is it neurotoxic? Neurobiol.Aging 13 591 PMID: 1281289
Schenk et al (1995) Therapeutic approaches related to amyloid-β peptide and Alzheimer's Disease J.Med.Chem. 38 4141 PMID: 7473539
Yankner et al (1990) Neurotrophic and neurotoxic effects of amyoid β protein: reversal by tachykinin neuropeptides. Science 250 279 PMID: 2218531
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关键词: Amyloid beta-peptide (25-35) (human), Amyloid beta-peptide (25-35) (human) supplier, Human, amyloid, β-protein, beta-protein, fragment, functionally, neurotoxicity, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, Secretase, Peptides, Amyloid, β-peptide, beta-peptide, (25-35), (human), amyloidbeta, amyloidb, Beta, 1429, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Amyloid β-peptide (25-35) (human) 的部分引用包括:
Ostrovskaya et al (2014) Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. J.Biomed.Sci. 21 74 PMID: 25096780
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