Amyloid β-peptide (25-35) (human)

Pricing Availability   Qty
说明: Human amyloid β-protein fragment functionally required for neurotoxicity
纯度: ≥95% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)

生物活性 for Amyloid β-peptide (25-35) (human)

Amyloid β-peptide (25-35) (human) is a fragment of human amyloid β-peptide, functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease.

技术数据 for Amyloid β-peptide (25-35) (human)

分子量 1060.27
公式 C45H81N13O14S
序列 GSNKGAIIGLM
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 131602-53-4
PubChem ID 10843733
InChI Key WIHBNMPFWRHGDF-SLVFWPMISA-N
Smiles [H]NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Amyloid β-peptide (25-35) (human)

溶解性 Soluble to 0.50 mg/ml in water

产品说明书 for Amyloid β-peptide (25-35) (human)

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参考文献 for Amyloid β-peptide (25-35) (human)

参考文献是支持产品生物活性的出版物。

Rush et al (1992) Intracerebral β-amyloid(25-35) produces tissue damage: is it neurotoxic? Neurobiol.Aging 13 591 PMID: 1281289

Schenk et al (1995) Therapeutic approaches related to amyloid-β peptide and Alzheimer's Disease J.Med.Chem. 38 4141 PMID: 7473539

Yankner et al (1990) Neurotrophic and neurotoxic effects of amyoid β protein: reversal by tachykinin neuropeptides. Science 250 279 PMID: 2218531


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关键词: Amyloid beta-peptide (25-35) (human), Amyloid beta-peptide (25-35) (human) supplier, Human, amyloid, β-protein, beta-protein, fragment, functionally, neurotoxicity, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, Secretase, Peptides, Amyloid, β-peptide, beta-peptide, (25-35), (human), amyloidbeta, amyloidb, Beta, 1429, Tocris Bioscience

1 篇 Amyloid β-peptide (25-35) (human) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Amyloid β-peptide (25-35) (human) 的部分引用包括:

Ostrovskaya et al (2014) Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. J.Biomed.Sci. 21 74 PMID: 25096780


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Alzheimer's Disease Poster

Alzheimer's Disease Poster

Alzheimer's disease (AD) is a debilitating and progressive neurodegenerative disease and the most common cause of dementia, affecting approximately 30% of individuals aged over 85 years. This poster summarizes the cellular and molecular mechanisms of AD.