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说明： Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release
化学名： Ammonium trichloro[1,2-ethanediolato-O,O']-tellurate
生物活性 for AS 101
AS 101 is an immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release.
技术数据 for AS 101
| 分子量 | 312.05 |
| 公式 | C2H4Cl3O2Te.NH4 |
| 储存 | Desiccate at RT |
| CAS Number | 106566-58-9 |
| PubChem ID | 24985142 |
| InChI Key | AXWLPMGUUAIGJK-UHFFFAOYSA-O |
| Smiles | [Cl-][Te+4]1([Cl-])([O-]CC[O-]1)[Cl-].[NH4+] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for AS 101
参考文献 for AS 101
参考文献是支持产品生物活性的出版物。
Kalechman et al (2004) Inhibition of interleukin-10 by the immunomodulator AS101 reduces mesangial cell proliferation in experimental mesangioproliferative glomerulonephritis. J.Biol.Chem. 279 24724 PMID: 15001575
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关键词: AS 101, AS 101 supplier, Immunomodulators, inhibits, inhibitors, IL-10, synthesis, potentiates, IL-1alpha, IL-2, TNFalpha, release, TNF-α, TNF-alpha, Interleukins, Tumor, Necrosis, Factor-α, Factor-alpha, Cytokines, Cytokine, NF-κB, NF-kappaB, Signaling, Signalling, AS101, 2446, Tocris Bioscience
1 篇 AS 101 的引用文献
引用文献是使用了 Tocris 产品的出版物。 AS 101 的部分引用包括：
Souza-Fonseca-Guimaraes et al (2012) NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis. J Immunol 188 5850 PMID: 22566566
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Rheumatoid Arthritis Poster
Rheumatoid arthritis (RA) is a chronic destructive inflammatory autoimmune disease that results from a breakdown in immune tolerance, for reasons that are as yet unknown. This poster summarizes the pathology of RA and the inflammatory processes involved, as well as describing some of the epigenetic modifications associated with the disease and the potential for targeting these changes in the discovery of new treatments.