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BOP-JF549

Cat. No. 6996 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6996 has been discontinued.

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说明： Yellow fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP conjugated to Janelia Fluor® 549; fluorogenic; photostable
化学名： 2-(3-(Azetidin-1-ium-1-ylidene)-6-(azetidin-1-yl)-3H-xanthen-9-yl)-4-(((1-((3R,5S)-5-(((S)-1-carboxy-2-(4-((pyrrolidine-1-carbonyl)oxy)phenyl)ethyl)carbamoyl)-1-(phenylsulfonyl)pyrrolidin-3-yl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)benzoate
纯度： ≥85% (HPLC)
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生物活性 Scientific Data 技术数据 说明书 参考文献

生物活性 for BOP-JF549

BOP-JF549 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP (Cat. No. 6047) conjugated to Janelia Fluor® 549 (Cat. No. 6147). Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long time-course experiments. Excitation maximum = 549 nm; emission maximum = 571 nm.

Scientific Data

Application of BOP-JF646 View Larger

Application of BOP-JF646 in Immortalized Human Keratinocyte Cells Immortalized human keratinocyte cells expressing a GFP-tagged alpha 4 integrin were treated with 10 μM BOP-Janelia Fluor® 646. Cells were incubated at 37°C and imaged using a Nikon A1R confocal microscope. Scale bar = 10 μm. Image kindly provided by Willow Hight-Warburton, Kings College London.

Optical Data for BOP-JF549

BOP-JF549 Dye Spectra
Emission Color Yellow
Brightness
λabs 549 nm
λem 571 nm
Closest Laser line 561 nm
Application Flow Cytometry, Confocal Microscopy, Super Resolution Microscopy (SRM)

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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技术数据 for BOP-JF549

分子量 1048.14
公式 C55H53N9O11S
储存 Store at -20°C
纯度 ≥85% (HPLC)
InChI Key CKYXWZFUNXSZMN-AYQWXEKZSA-N
Smiles OC([C@H](CC1=CC=C(OC(N2CCCC2)=O)C=C1)NC([C@@H]3C[C@H](CN3S(=O)(C4=CC=CC=C4)=O)N5C=C(N=N5)CNC(C6=CC=C(C(C(C7=CC=C(C=C7OC8=C/9)N%10CCC%10)=C8C=CC9=[N+]%11CCC/%11)=C6)C([O-])=O)=O)=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for BOP-JF549

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关键词: BOP-JF549, BOP-JF549 supplier, Yelllow, fluorescent, dual, α9β1/α4β1, integrins, inhibitors, BOP, labels, stains, HSC, progenitors, hematopoietic, stem, cells, Stem, Cell, Signaling, Integrins, Fluorescent, Integrin, Probes, Hematopoietic, Cells, 6996, Tocris Bioscience

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including Janelia Fluor® Dyes
  • Fluorescent Probes for Advanced Microscopy and Live Cell Imaging
  • Fluorescent Probes to Support In Vivo, Deep Tissue, and Bioluminescence Imaging
  • Fluorescent Probes and Reagents for Organoids and 3D Cell Culture Imaging
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals
  • Tissue Clearing Kits and Reagents