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Submit ReviewBRD 9876
说明： ATP non-competitive kinesin Eg5 inhibitor
化学名： 6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile
纯度： ≥99% (HPLC)
生物活性 for BRD 9876
ATP non-competitive kinesin Eg5 inhibitor. Selectively inhibits microtubule-bound Eg5. Inhibits multiple myeloma cell growth (IC50 = 2.2 μM).
技术数据 for BRD 9876
| 分子量 | 234.3 |
| 公式 | C16H14N2 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 32703-82-5 |
| PubChem ID | 613000 |
| InChI Key | MKILROQBJOOZKC-UHFFFAOYSA-N |
| Smiles | CC(C)(C)C2=CC1=CC(C#N)=C(C#N)C=C1C=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for BRD 9876
参考文献 for BRD 9876
参考文献是支持产品生物活性的出版物。
Chattopadhyay et al (2015) Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitors. Cell Rep. 10 755 PMID: 25660025
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关键词: BRD 9876, BRD 9876 supplier, BRD9876, ATP, non-competitive, kinesin-5, Eg5, inhibitors, inhibits, microtubule-bound, Kinesin, Mitosis, 5454, Tocris Bioscience
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Cell Cycle and DNA Damage Research Product Guide
This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:
- Cell Cycle and Mitosis
- DNA Damage Repair
- Targeted Protein Degradation
- Ubiquitin Proteasome Pathway
- Chemotherapy Targets