Butabindide oxalate

Name: Butabindide oxalate
Brand: Tocris Bioscience
SKU: 1323

Cat. No. 1323 3 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1323 has been discontinued.

View all Other Proteases products.

说明： High affinity CCK-inactivating serine protease inhibitor

化学名： (2S)-[1-[(2S)-2-amino-1-oxobutyl]-N-butyl]-2,3-dihydro-1H-indole-2-carboxamide oxalate

纯度： ≥99% (HPLC)

说明书

引用文献 (3)

生物活性技术数据说明书参考文献

生物活性 for Butabindide oxalate

Butabindide oxalate is a high affinity, reversible, selective and competitive inhibitor of a CCK-inactivating serine protease (tripeptidyl peptidase II) (K_i = 7 nM). Active in vivo (ID₅₀ = 1.1 and 6.8 mg/kg i.v. for inhibition of liver and brain enzyme respectively).

许可信息

Sold with the permission of INSERM and UCL

技术数据 for Butabindide oxalate

分子量	393.44
公式	C₁₇H₂₅N₃O₂.C₂H₂O₄
储存	Desiccate at -20°C
纯度	≥99% (HPLC)
CAS Number	185213-03-0
PubChem ID	56972132
InChI Key	KKMJFDVOXSGHBF-SLHAJLBXSA-N
Smiles	O=C(O)C(O)=O.O=[C@]([C@@H](N)CC)N([C@H]([C@@](NCCCC)=O)C2)C1=C2C=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Butabindide oxalate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Butabindide oxalate

参考文献是支持产品生物活性的出版物。

Ganellin et al (2000) Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J.Med.Chem. 43 664 PMID: 10691692

Renn et al (1998) Characterization and cloning of tripeptidyl peptidase II from the fruit fly, Drosophila melanogaster. J.Biol.Chem. 273 19173 PMID: 9668104

Rose et al (1996) Characterization and inhibition of a cholecystokinin-inactivating serine peptidase. Nature 380 403 PMID: 8602240

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关键词: Butabindide oxalate, Butabindide oxalate supplier, CCK-inactivating, serine, protease, inhibitors, inhibits, tripeptidyl, peptidase, II, Proteases, Proteinases, Cholecystokinin, Other, Non-selective, CCK, 1323, Tocris Bioscience