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Dansyl-NECA

Cat. No. 5122 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5122 has been discontinued.

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说明： Potent and selective fluorescent adenosine A1 agonist
化学名： 1-Deoxy-1-[6-[[6-[[[5-dimethylamino)-1-naphthalenyl]sulfonyl]amino]hexyl]amino]-9H-purin-9-yl]-N-ethyl-β-D-ribofuranuronamide
纯度： ≥99% (HPLC)
说明书
引用文献
评论
文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性 for Dansyl-NECA

Dansyl-NECA is a high affinity and selective fluorescent adenosine A1 receptor agonist (Ki values are 27, 3600 and 4300 nM for A1, A3 and A2 receptors, respectively). Permits visualization of A1 receptors in the rat cerebellar cortex.

技术数据 for Dansyl-NECA

分子量 640.75
公式 C30H40N8O6S
储存 Store at -20°C
纯度 ≥99% (HPLC)
CAS Number 219982-12-4
PubChem ID 10009321
InChI Key CJDPJPUVKHWZHU-YRIIQKNPSA-N
Smiles CN(C)C1=C2C(C(S(NCCCCCCNC3=NC=NC4=C3N=CN4[C@H]5[C@H](O)[C@H](O)[C@@H]([C@@](NCC)=O)O5)(=O)=O)=CC=C2)=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Dansyl-NECA

参考文献是支持产品生物活性的出版物。

Macchia et al (1998) Fluorescent probes for adenosine receptors: synthesis and biology of N6-dansylaminoalkyl-substituted NECA derivatives. Bioorg. Med. Chem. Lett. 8 3223 PMID: 9873707

Kozma et al (2013) Fluorescent ligands for adenosine receptors. Bioorg. Med. Chem. Lett. 23 26 PMID: 23200243

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关键词: Dansyl-NECA, Dansyl-NECA supplier, Dansyl, NECA, potent, selective, fluorescent, adenosine, A1, agonist, Adenosine, Receptors, Fluorescent, Receptor, Probes, 5122, Tocris Bioscience

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
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  • Fluorescent Probes for Imaging Bacteria
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Enabling Research By Provision of Chemical Tools Poster

Enabling Research By Provision of Chemical Tools Poster

The Tocris chemistry team has considerable chemistry knowledge and skill which it has recently been applying to the generation of new chemical probes from known tools and compounds to help answer biological questions. This poster presents some of the work carried out by Tocris scientists and focuses on two areas: the generation of libraries of chemical building blocks to support Degrader (PROTAC) research and the development of a fluorescent probe to study integrin biology. Presented at Chemical Tools for Complex Biological Systems II, 2019, Janelia Research Campus, USA.