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FFN 102 mesylate

Cat. No. 5200 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Selective fluorescent substrate of DAT and VMAT2
化学名： 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one methanesulfonate
纯度： ≥99% (HPLC)
说明书
引用文献
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生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for FFN 102 mesylate

FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.

许可信息

Sold with the permission of Columbia University.

技术数据 for FFN 102 mesylate

分子量 335.76
公式 C11H11N2ClO3.CH3SO3H
储存 Desiccate at +4°C
纯度 ≥99% (HPLC)
CAS Number 1883548-92-2
PubChem ID 91691121
InChI Key ZEZDFYRVIVZPAT-UHFFFAOYSA-N
Smiles ClC1=C(O)C=C(OC(C=C2CCN)=O)C2=C1.CS(=O)(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for FFN 102 mesylate

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 6.72 20 温和加热
DMSO 33.58 100

制备储备液 for FFN 102 mesylate

以下数据基于产品分子量 335.76。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.98 mL 14.89 mL 29.78 mL
5 mM 0.6 mL 2.98 mL 5.96 mL
10 mM 0.3 mL 1.49 mL 2.98 mL
50 mM 0.06 mL 0.3 mL 0.6 mL

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产品说明书 for FFN 102 mesylate

分析证书/产品说明书
化学品安全技术说明书

参考文献 for FFN 102 mesylate

参考文献是支持产品生物活性的出版物。

Rodriguez et al (2013) Fluorescent DA tracer resolves individual DArgic synapses and their activity in the brain. Proc.Natl.Acad.Sci.U.S.A. 110 870 PMID: 23277566

Sames et al (2013) Visualizing neurotransmitter secretion at individual synapses. ACS Chem.Neurosci. 4 648 PMID: 23862751

Lee et al (2010) Development of pH-responsive fluorescent false neurotransmitters. J.Am.Chem.Soc. 132 8828 PMID: 20540519

If you know of a relevant reference for FFN 102 mesylate, please let us know.

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

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