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GSK 2018682

Cat. No. 6709 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： S1P1 and S1P5 agonist
化学名： 4-[5-[5-Chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-1H-indole-1-butanoic acid
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for GSK 2018682

GSK 2018682 is a sphingosine-1-phosphate receptor 1 (S1P1) and 5 (S1P5) agonist.

化合物库 for GSK 2018682

GSK 2018682 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for GSK 2018682

分子量 440.88
公式 C22H21ClN4O4
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1034688-30-6
PubChem ID 24988201
InChI Key NFIGDBFIDKDNIG-UHFFFAOYSA-N
Smiles CC(OC1=NC=C(C2=NC(C3=C4C=CN(C4=CC=C3)CCCC(O)=O)=NO2)C=C1Cl)C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for GSK 2018682

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 44.09 100

制备储备液 for GSK 2018682

以下数据基于产品分子量 440.88。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.27 mL 11.34 mL 22.68 mL
5 mM 0.45 mL 2.27 mL 4.54 mL
10 mM 0.23 mL 1.13 mL 2.27 mL
50 mM 0.05 mL 0.23 mL 0.45 mL

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参考文献 for GSK 2018682

参考文献是支持产品生物活性的出版物。

Bigaud et al (2014) Second generation S1P pathway modulators: research strategies and clinical developments. Biochim.Biophys.Acta. 1841 745 PMID: 24239768

Subei and Cohen (2015) Sphingosine 1-phosphate receptor modulators in multiple sclerosis. CNS.Drugs. 29 565 PMID: 26239599

If you know of a relevant reference for GSK 2018682, please let us know.

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关键词: GSK 2018682, GSK 2018682 supplier, GSK2018682, S1P1, S1P5, receptor, agonists, agonism, Sphingosine-1-phosphate, Receptors, 6709, Tocris Bioscience

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