Leupeptin hemisulfate

Name: Leupeptin hemisulfate
Brand: Tocris Bioscience
SKU: 1167
Rating: 5 (1 reviews)

Cat. No. 1167 2 篇引用文献 1 条评论提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Inhibits trypsin-like/cysteine proteases

纯度： ≥95% (HPLC)

说明书

引用文献 (2)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Leupeptin hemisulfate

Leupeptin hemisulfate is a reversible inhibitor of trypsin-like and cysteine proteases such as calpain. Shown to inhibit activation-induced programmed cell death.

技术数据 for Leupeptin hemisulfate

分子量	475.6
公式	C₂₀H₃₈N₆O₄.½H₂SO₄
序列	LLR (Modifications: Leu-1 = N-terminal Ac, Arg-3 = Arginal)
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	103476-89-7
PubChem ID	2733491
InChI Key	CIPMKIHUGVGQTG-VFFZMTJFSA-N
Smiles	OS(O)(=O)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Leupeptin hemisulfate

溶解性	Soluble to 10 mg/ml in water

产品说明书 for Leupeptin hemisulfate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Leupeptin hemisulfate

参考文献是支持产品生物活性的出版物。

Mehdi (1991) Cell-penetrating inhibitors of calpain. TiBS 16 150 PMID: 1877091

Sarin et al (1994) Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors. J.Immunol. 153 862 PMID: 8021517

Wang (1990) Developing selective inhibitors of calpain. TiPS 11 139 PMID: 2185586

If you know of a relevant reference for Leupeptin hemisulfate, please let us know.

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关键词: Leupeptin hemisulfate, Leupeptin hemisulfate supplier, inhibitors, inhibits, trypsin-like, cysteine, proteases, Proteases, Proteinases, Other, 1167, Tocris Bioscience

2 篇 Leupeptin hemisulfate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Leupeptin hemisulfate 的部分引用包括：

Berg et al (2019) Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation. Cell Rep 27 2837 PMID: 31167131

Haller et al (2015) Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity. J Pharmacol Exp Ther 10 2269 PMID: 25629932

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