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Submit ReviewLPYFD-NH2
Discontinued Product
4084 has been discontinued.
说明： Binds Aβ; protects from aggregation induced toxicity
生物活性 for LPYFD-NH2
LPYFD-NH2 is a neuroprotective peptide that binds to amyloid beta (Aβ). Protects neurons against toxic effects of Aβ (1-42) in vitro and in vivo. Potential therapeutic in the treatment of Alzheimer's Disease.
技术数据 for LPYFD-NH2
| 分子量 | 652.75 |
| 公式 | C33H44N6O8 |
| 序列 |
LPYFD-NH2 (Modifications: Asp-5 = C-terminal amide) |
| 储存 | Store at -20°C |
| CAS Number | 700361-48-4 |
| PubChem ID | 90488910 |
| InChI Key | IZXBZWOUOODINS-IRGGMKSGSA-N |
| Smiles | [H]N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for LPYFD-NH2
参考文献 for LPYFD-NH2
参考文献是支持产品生物活性的出版物。
Szegedi et al (2005) Pentapeptides derived from Aβ1-42 protect neurons from the modulatory effects of Aβ fibrils- an in vitro and in vivo electrophysiological study. Neurobiology of Disease 18 499 PMID: 15755677
Juhasz et al (2009) An intraperitoneally administered pentapeptide protects against Aβ (1-42) induced neuronal excitation in vivo. J.Alzheimer's Dis. 16 189
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关键词: LPYFD-NH2, LPYFD-NH2 supplier, LPYFDNH2, neuroprotective, amyloid, sequence-derived, peptides, binds, beta, Ab, Aβ, Alzheimers, amyloidbeta, amyloidb, amyloidβ, Amyloid, Beta, Peptides, 4084, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Alzheimer's Disease Poster
Alzheimer's disease (AD) is a debilitating and progressive neurodegenerative disease and the most common cause of dementia, affecting approximately 30% of individuals aged over 85 years. This poster summarizes the cellular and molecular mechanisms of AD.