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Minoxidil

Cat. No. 0583 1 次引用 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Kir6 channel (KATP) opener
化学名： 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Minoxidil

Minoxidil is an antihypertensive. Antialopecia agent. Kir6 channel (KATP) activator.

化合物库 for Minoxidil

Minoxidil is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。

技术数据 for Minoxidil

分子量 209.25
公式 C9H15N5O
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 38304-91-5
PubChem ID 4201
InChI Key ZIMGGGWCDYVHOY-UHFFFAOYSA-N
Smiles NC1=CC(=NC(N)=[N+]1[O-])N1CCCCC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Minoxidil

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
ethanol 5.23 25
DMSO 5.23 25 温和加热

制备储备液 for Minoxidil

以下数据基于产品分子量 209.25。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.25 mM 19.12 mL 95.58 mL 191.16 mL
1.25 mM 3.82 mL 19.12 mL 38.23 mL
2.5 mM 1.91 mL 9.56 mL 19.12 mL
12.5 mM 0.38 mL 1.91 mL 3.82 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Dilution Calculator

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产品说明书 for Minoxidil

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Minoxidil

参考文献是支持产品生物活性的出版物。

Lachgar et al (1998) Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells. Br.J.Dermatol. 138 407 PMID: 9580790

Meisheri et al (1993) Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil. Biochem.Pharmacol. 45 271 PMID: 8435087

Tsoporis et al (1993) Effects of the arterial vasodilator minoxidil on cardiovascular structure and sympathetic activity in spontaneously hypertensive rats. J.Hypertens. 11 1337 PMID: 8133016

Merck Index 12 6290

If you know of a relevant reference for Minoxidil, please let us know.

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关键词: Minoxidil, Minoxidil supplier, K+, channel, KATP, openers, Potassium, KIR, Channels, Inward, Rectifier, antihypertensive, activators, Kir6, rectifier, 0583, Tocris Bioscience

1 篇 Minoxidil 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Minoxidil 的部分引用包括：

Sun et al (2014) Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel. Sci Rep 4 4934 PMID: 24816792

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Minoxidil 的评论

平均评分: 5 (Based on 1 Review.)

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Minoxidil used to study BK channel opening.
By Sadequl Islam on 11/27/2018
分析类型： In Vitro
种属： Human

Minoxidil was used based on its history as a potent potassium channel opener. It was used to study BK channel opening.

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