Myelin Basic Protein (87-99)

Name: Myelin Basic Protein (87-99)
Brand: Tocris Bioscience
SKU: 3399

Cat. No. 3399 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3399 has been discontinued.

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说明： Major antigenic component implicated in the pathophysiology of multiple sclerosis

纯度： ≥95% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Myelin Basic Protein (87-99)

Myelin Basic Protein (87-99) is an encephalitogenic peptide that induces T cell proliferation with Th1 polarization in the CNS. Major antigenic component implicated in the pathophysiology of multiple sclerosis.

技术数据 for Myelin Basic Protein (87-99)

分子量	1555.8
公式	C₇₄H₁₁₄N₂₀O₁₇
序列	VHFFKNIVTPRTP
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	118506-26-6
PubChem ID	25077562
InChI Key	XSSZRUKIAIQNAZ-SAKFXWCOSA-N
Smiles	[H]N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Myelin Basic Protein (87-99)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Myelin Basic Protein (87-99)

参考文献是支持产品生物活性的出版物。

Jones et al (1992) The synthetic 87-99 peptide of myelin basic protein is encelphalitogenic in Buffalo rats. J.Neuroimmunol. 37 203 PMID: 1373154

Deraos et al (2008) Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP87-99) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: Implications in triggering disease. J.Med.Chem. 51 7834 PMID: 19053745

Hofstetter et al (2005) Does the frequency and avidity spectrum of the neuroantigen-specific T cells in the blood mirror the autoimmune process in the central nervous system of mice undergoing experimental allergic encephalomyelitis? J.Immunol. 22 4598

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关键词: Myelin Basic Protein (87-99), Myelin Basic Protein (87-99) supplier, antigenic, component, implicated, pathophysiology, multiple, sclerosis, Encephalitogenic, peptide, Neuronal, Metabolism, Miscellaneous, Compounds, 3399, Tocris Bioscience

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