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PKC (19-36)

Cat. No. 4058 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4058 has been discontinued.

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说明： Pseudosubstrate peptide; inhibitor of PKC
说明书
引用文献 (1)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for PKC (19-36)

Pseudosubstrate peptide inhibitor of protein kinase C (IC50 = 0.18 μM). Attenuates vascular hyperproliferation and hypertrophy induced by high glucose. Inhibits DNA and protein synthesis in vascular smooth muscle cells (VSMCs) in a dose-dependent manner.

Negative Control also available.

技术数据 for PKC (19-36)

分子量 2151.48
公式 C93H159N35O24
序列 RFARKGALRQKNVHEVKN
储存 Store at -20°C
CAS Number 113731-96-7
PubChem ID 71308428
InChI Key NHCJMYZDRROLEW-OFXZVSIYSA-N
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for PKC (19-36)

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for PKC (19-36)

参考文献是支持产品生物活性的出版物。

Yasunari et al (1996) Possible involvement of phospholipase D and protein kinase C in vascular growth induced by elevated glucose concentration Hypertension 28 159 PMID: 8707376

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关键词: PKC (19-36), PKC (19-36) supplier, PKC, inhibitors, inhibits, pseudosubstrate, protein, kinase, C, fragment, (19-36), PKCI, Protein, Kinase, 4058, Tocris Bioscience

1 篇 PKC (19-36) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 PKC (19-36) 的部分引用包括：

Glovaci and Chapman (2015) Activation of Phosphatidylinositol-Linked DA Receptors Induces a Facilitation of Glutamate-Mediated Synaptic Transmission in the Lateral Entorhinal Cortex. Mol Med Rep 10 e0131948 PMID: 26133167

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