(R)-(+)-Blebbistatin

Discontinued Product

1853 has been discontinued.

View all Myosin products.
说明: Selective inhibitor of myosin II ATPase activity. Inactive enantiomer of (±)-blebbistatin (Cat. No. 1760)
化学名: (3aR)-(+)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one
纯度: ≥99% (HPLC)
说明书
引用文献 (3)
评论

生物活性 for (R)-(+)-Blebbistatin

(R)-(+)-Blebbistatin is an inactive enantiomer of the selective inhibitor of myosin II (±)-blebbistatin.

Active Enantiomer and Racemate also available.

技术数据 for (R)-(+)-Blebbistatin

分子量 292.34
公式 C18H16N2O2
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 1177356-70-5
PubChem ID 6604910
InChI Key LZAXPYOBKSJSEX-SFHVURJKSA-N
Smiles O=C2[C@]3(O)C(N(C4=CC=CC=C4)CC3)=NC1=CC=C(C)C=C12

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for (R)-(+)-Blebbistatin

分析证书/产品说明书
选择另一批次:

参考文献 for (R)-(+)-Blebbistatin

参考文献是支持产品生物活性的出版物。

Limouze et al (2004) Specificity of blebbistatin, an inhibitor of myosin II. J.Muscle Res.Cell Motil. 25 337 PMID: 15548862

Straight et al (2003) Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor. Science 299 1743 PMID: 12637748

Straight et al (2002) Dissecting cytokinesis with small molecules. Amer.Soc.Cell Biol.Abstr. 2515

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关键词: (R)-(+)-Blebbistatin, (R)-(+)-Blebbistatin supplier, Selective, inhibitors, inhibits, myosin, II, ATPase, (R)-(+)-Blebbistatin, Myosin, 1853, Tocris Bioscience

3 篇 (R)-(+)-Blebbistatin 的引用文献

引用文献是使用了 Tocris 产品的出版物。 (R)-(+)-Blebbistatin 的部分引用包括:

Nyholm et al (2009) A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation. J Cell Sci 122 2137 PMID: 19470582

Maître et al (2016) Asymmetric division of contractile domains couples cell positioning and fate specification. Nature 536 344 PMID: 27487217

Bzymek et al (2016) Real-time two- and three-dimensional imaging of monocyte motility and navigation on planar surfaces and in collagen matrices: roles of Rho. Sci Rep 6 25016 PMID: 27122054


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