Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewRMR-Tre
说明： Far-red fluorogenic trehalose probe for live mycobacteria imaging
化学名： 3-(6-(5-(2,2-Dicyanovinyl)thiophen-2-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-(((2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)methyl)propanamide
纯度： ≥95% (HPLC)
生物活性 for RMR-Tre
RMR-Tre is a far-red fluorogenic trehalose specific probe for live mycobacteria imaging. It enables fast, no-wash, low-background fluorescence detection of live mycobacterial outer membrane. RMR-Tre contains a molecular rotor fluorophore that brightly emits signal in the far-red region upon trehalose-guided metabolic integration into the mycomembrane. It exhibited up to a 100- fold enhancement in Mycobacterium tuberculosis labeling compared to existing fluorogenic trehalose probes. Excitation and emission maxima (λ) are 549 nm and 571 nm, respectively.
Scientific Data
Fluorescence Imaging
View Larger
View Larger
Application of RMR-Tre. Image shows fluorescence detection of live mycobacterial outer membrane: M. smegmatis were incubated for 1 h in the presence of 100 μM of RMR-Tre, then directly imaged by fluorescence microscopy without washing. Scale bar: 10 μm.
许可信息
Sold under license from Central Michigan University
Optical Data for RMR-Tre
| Emission Color | Far Red |
|---|---|
| λabs | 536 nm |
| λem | 684 nm |
| Closest Laser line | 540 nm |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectral Viewer
技术数据 for RMR-Tre
| 分子量 | 686.73 |
| 公式 | C32H38N4O11S |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| PubChem ID | 172005912 |
| InChI Key | SSAVIDOUSMJZDG-IVJDZZAPSA-N |
| Smiles | O[C@H]1[C@@H]([C@H]([C@H](O[C@@H]1CO)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CNC(CCN3C4=C(CCC3)C=C(C5=CC=C(S5)/C=C(C#N)/C#N)C=C4)=O)O)O)O)O)O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for RMR-Tre
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| DMSO | 6.87 | 10 |
制备储备液 for RMR-Tre
以下数据基于产品分子量 686.73。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.56 mL | 72.81 mL | 145.62 mL |
| 0.5 mM | 2.91 mL | 14.56 mL | 29.12 mL |
| 1 mM | 1.46 mL | 7.28 mL | 14.56 mL |
| 5 mM | 0.29 mL | 1.46 mL | 2.91 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
产品说明书 for RMR-Tre
参考文献 for RMR-Tre
参考文献是支持产品生物活性的出版物。
Banahene et al (2023) A far-red molecular rotor fluorogenic trehalose probe for live mycobacteria detection and drug-susceptibility testing. Angew.Chem.Int.Ed.Engl. 62 e202213563 PMID: 36346622
If you know of a relevant reference for RMR-Tre, please let us know.
关键词: RMR-Tre, RMR-Tre supplier, fluorescent, labeling, bacteria, labels, labelling, red, probes, for, imaging, trehalose, live, mycobacteria, fluorophore, Fluorescent, Probes, Imaging, Bacteria, 8013, Tocris Bioscience
RMR-Tre 的评论
目前没有该产品的评论。 Be the first to review RMR-Tre and earn rewards!
Have you used RMR-Tre?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Fluorescent Dyes and Probes Research Product Guide
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
- Fluorescent Dyes, including dyes for flow cytometry
- Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
- Tissue Clearing Kits and Reagents
- Aptamer-based RNA Imaging Reagents
- Fluorescent Probes for Imaging Bacteria
- TSA VividTM Fluorophore Kits
- TSA Reagents for Enhancing IHC, ICC & FISH Signals