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S3QEL 2

Cat. No. 5735 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5735 has been discontinued.

说明： Suppressor of complex III superoxide production
化学名： 1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
纯度： ≥98% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for S3QEL 2

Suppresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation (IC50 = 1.7 μM). Suppresses HIF-1α accumulation and enhances survival and function of primary pancreatic islets in vitro. Cell permeable.

技术数据 for S3QEL 2

分子量 323.44
公式 C19H25N5
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 890888-12-7
PubChem ID 17017624
InChI Key MGIAJZSCNPODRR-UHFFFAOYSA-N
Smiles CC(C(C)=C1)=CC=C1N2C3=NC=NC(N(CCC)CCC)=C3C=N2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for S3QEL 2

参考文献是支持产品生物活性的出版物。

Orr et al (2015) Suppressors of superoxide production from mitochondrial complex III. Nat.Chem.Biol. 11 834 PMID: 26368590

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关键词: S3QEL 2, S3QEL 2 supplier, S3QEL2, Suppresses, superoxide, production, complex, III, mitochondria, oxidative, phosphorylation, ROS, reactive, oxygen, species, inhibitors, inhibits, Donors, Oxidative, Phosphorylation, 5735, Tocris Bioscience

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