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Submit ReviewSCOTfluor 510 Fmoc-Dapa-OH New
Description: Fmoc protected fluorescent amino acid for use in solid-phase peptide synthesis to prepare PAINT imaging probes
Chemical Name: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((7-nitrobenzo[c][1,2,5]selenadiazol-4-yl)amino) propanoic acid
Purity: ≥95% (HPLC)
Biological Activity for SCOTfluor 510 Fmoc-Dapa-OH
SCOTfluor 510 Fmoc-Dapa-OH is a Fmoc protected fluorescent amino acid. Used as a building block in solid-phase peptide synthesis to prepare PAINT imaging probes.
Application: use in solid-phase peptide synthesis (SPPS) for PAINT imaging.
Properties and Photophysical Data: excitation and emission maxima (λ) are 488 nm and 601 nm, respectively; quantum yield = 0.19; extinction coefficient = 4,480 M-1cm-1.
Licensing Information
Sold under license from the University of Edinburgh
Usage Guidelines for SCOTfluor 510 Fmoc-Dapa-OH
This product is provided for use in onward chemistry. Suitable solvents can be used.
Optical Data for SCOTfluor 510 Fmoc-Dapa-OH
| Emission Color | Orange |
|---|---|
| λabs | 488 nm |
| λem | 601 nm |
| Extinction Coefficient (ε) | 4480 M-1cm-1 |
| Quantum Yield (φ) | 0.19 |
| Closest Laser line | 488 nm |
| Application | Solid-phase peptide synthesis, SPPS, peptide-PAINT |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectral Viewer
Technical Data for SCOTfluor 510 Fmoc-Dapa-OH
| M. Wt | 552.41 |
| Formula | C24H19N5O6Se |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 3023933-33-4 |
| PubChem ID | 171367848 |
| InChI Key | VAXPLXAQQDLVTP-IBGZPJMESA-N |
| Smiles | O=[N+](C1=CC=C(C2=N[Se]N=C21)NC[C@H](NC(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)C(O)=O)[O-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for SCOTfluor 510 Fmoc-Dapa-OH
References for SCOTfluor 510 Fmoc-Dapa-OH
References are publications that support the biological activity of the product.
de Moliner et al (2023) Small fluorogenic amino acids for peptide-guided background-free imaging. Angew.Chem.Int.Ed.Engl. 62 e202216231 PMID: 36412996
If you know of a relevant reference for SCOTfluor 510 Fmoc-Dapa-OH, please let us know.
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