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SBP1-FITC

Cat. No. 7232 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

7232 has been discontinued.

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说明： Fluorescent ACE2-derived peptide; binds receptor binding domain of SARS-CoV-2 spike protein
纯度： ≥95% (HPLC)
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引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for SBP1-FITC

SBP1-FITC is a fluorescently labelled peptide derived from human ACE2 (SBP1, Cat. No. 7233). Composed of SBP1 conjugated to FITC (Fluorescein-5-isothiocyanate; Cat. No. 5440). SBP1 binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication).

Please note - unpublished, in-house data suggests SBP1 has approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.

技术数据 for SBP1-FITC

分子量 3438.68
公式 C159H217N33O51S
序列 IEEQAKTFLDKFNHEAEDLFYQS

(Modifications: Ile-1 = FITC-PEG4-Ile, Ser-23 = C-terminal amide)
储存 Store at -20°C
纯度 ≥95% (HPLC)
InChI Key XEJQYVVTMPCYCP-TVTAXLCZSA-N
Smiles O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(N)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)NC(CCOCCOCCOCCOCCNC(NC(C=C6C(O)=O)=CC=C6C(C7=CC=C(O)C=C7O8)=C(C=C9)C8=CC9=O)=S)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for SBP1-FITC

参考文献是支持产品生物活性的出版物。

Zhang et al (2020) The first-in-class peptide binder to the SARS-CoV-2 spike protein. BioRxiv - Paper not yet peer reviewed.

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