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Suplatast tosylate

Cat. No. 3543 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3543 has been discontinued.

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说明： Th2 cytokine synthesis inhibitor; antiasthmatic
别名： IPD 1151T
化学名： [3-[[4-(3-Ethoxy-2-hydroxypropoxy)phenyl]amino]-3-oxopropyl]dimethylsulfonium 4-methylbenzenesulfonate
纯度： ≥99% (HPLC)
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引用文献
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文献 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for Suplatast tosylate

Suplatast tosylate is a th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production. Acts as an immunoregulator that suppresses IgE production, eosinophil infiltration and histamine release. Exhibits antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active.

技术数据 for Suplatast tosylate

分子量 499.64
公式 C16H26NO4S.C7H7O3S
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 94055-76-2
PubChem ID 71773
InChI Key RYVJQEZJUFRANT-UHFFFAOYSA-N
Smiles O=C(CC[S+](C)C)NC1=CC=C(OCC(O)COCC)C=C1.CC2=CC=C(S(=O)([O-])=O)C=C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Suplatast tosylate

分析证书/产品说明书
化学品安全技术说明书

参考文献 for Suplatast tosylate

参考文献是支持产品生物活性的出版物。

Kurokawa et al (2001) Suppressive effects of anti-allergic agent suplatast tosilate (IPD-1151T) on the expression of co-stimulatory molecules on mouse splenocytes in vivo. Mediators Inflamm. 10 333 PMID: 11817674

Hsu et al (2007) The effects of suplatast tosilate (IPD-1151T) on innate immunity and antigen-presenting cells. Transpl.Immunol. 18 108 PMID: 18005853

Furonaka et al (2009) Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice. J.Pharmacol.Exp.Ther. 328 55 PMID: 18832650

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关键词: Suplatast tosylate, Suplatast tosylate supplier, Th2, cytokine, synthesis, inhibitors, inhibits, antiasthmatic, TNF-α, TNF-alpha, Interleukins, Tumor, Necrosis, Factor-α, Factor-alpha, Cytokines, Cytokine, NF-κB, NF-kappaB, Signaling, Signalling, IPD1151T, IPD, 1151T, 3543, Tocris Bioscience

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