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Surfen

Cat. No. 6634 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Heparin sulfate antagonist
化学名： N,N'-Bis(4-amino-2-methyl-6-quinolinyl)urea dihydrochloride
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Surfen

Surfen is a heparan sulfate antagonist. Inhibits heparan sulfate-mediated cell attachment in vitro. Maintains hESCs in a pluripotent state by reversible inhibition of glycan-growth factor interactions.

化合物库 for Surfen

Surfen is also offered as part of the Tocriscreen Stem Cell Library. 了解 Tocris 化合物库的更多信息。

技术数据 for Surfen

分子量 445.35
公式 C21H20N6O.2HCl
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 5424-37-3
PubChem ID 79472
InChI Key GKQYGRWQCWWSHN-UHFFFAOYSA-N
Smiles CC1=NC2=CC=C(C=C2C(N)=C1)NC(NC3=CC=C4N=C(C=C(C4=C3)N)C)=O.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Surfen

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 8.91 20
DMSO 8.91 20

制备储备液 for Surfen

以下数据基于产品分子量 445.35。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.2 mM 11.23 mL 56.14 mL 112.27 mL
1 mM 2.25 mL 11.23 mL 22.45 mL
2 mM 1.12 mL 5.61 mL 11.23 mL
10 mM 0.22 mL 1.12 mL 2.25 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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参考文献 for Surfen

参考文献是支持产品生物活性的出版物。

Schuksz et al (2008) Surfen, a small molecule antagonist of heparan sulfate. Proc.Natl.Acad.Sci.USA 105 13074 PMID: 18725627

Huang et al (2018) Small molecule antagonist of cell surface glycosaminoglycans restricts mouse embryonic stem cells in a pluripotent state. Stem Cells. 36 45 PMID: 28984039

If you know of a relevant reference for Surfen, please let us know.

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关键词: Surfen, Surfen supplier, human, embryonic, stem, cells, pluripotency, hECS, HS, heparin, sulfate, sulphate, antagonists, antagonism, Cell, Adhesion, Molecules, Stem, Proliferation, 6634, Tocris Bioscience

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