TM 5275 sodium salt

Cat. No. 5769 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Plasminogen activator inhibitor-1 (PAI-1) inhibitor; orally bioavailable

化学名： 5-Chloro-2-[[2-[2-[4-(Diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt

纯度： ≥98% (HPLC)

引用文献 (1)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for TM 5275 sodium salt

TM 5275 sodium salt is a plasminogen activator inhibitor-1 (PAI-1) inhibitor. Orally bioavailable.

化合物库 for TM 5275 sodium salt

TM 5275 sodium salt is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for TM 5275 sodium salt

分子量	543.97
公式	C₂₈H₂₇ClN₃NaO₅
储存	Store at +4°C
纯度	≥98% (HPLC)
CAS Number	1103926-82-4
PubChem ID	53240409
InChI Key	JSHSGBIWNPQCQZ-UHFFFAOYSA-M
Smiles	O=C(COCC(NC4=C(C(O[Na])=O)C=C(Cl)C=C4)=O)N1CCN(C(C3=CC=CC=C3)C2=CC=CC=C2)CC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for TM 5275 sodium salt

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	54.4	100

制备储备液 for TM 5275 sodium salt

以下数据基于产品分子量 543.97。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	1.84 mL	9.19 mL	18.38 mL
5 mM	0.37 mL	1.84 mL	3.68 mL
10 mM	0.18 mL	0.92 mL	1.84 mL
50 mM	0.04 mL	0.18 mL	0.37 mL

Molarity Calculator

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产品说明书 for TM 5275 sodium salt

分析证书/产品说明书

化学品安全技术说明书

参考文献 for TM 5275 sodium salt

参考文献是支持产品生物活性的出版物。

Yamaoka et al (2011) Structure-activity relationships of new N-acylanthranilic acid derivatives as plasminogen activator inhibitor-1 inhibitors. Chem.Pharm.Bull. 59 215 PMID: 21297302

If you know of a relevant reference for TM 5275 sodium salt, please let us know.

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1 篇 TM 5275 sodium salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 TM 5275 sodium salt 的部分引用包括：

Sun-Hee et al (2022) Secretory SERPINE1 Expression Is Increased by Antiplatelet Therapy, Inducing MMP1 Expression and Increasing Colon Cancer Metastasis. Int J Mol Sci 23 PMID: 36076991

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