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UCLA GP130 2

Cat. No. 6583 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： gp130 agonist; brain penetrant and neuroprotectant
化学名： N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine
纯度： ≥98% (HPLC)
说明书
引用文献
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文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for UCLA GP130 2

UCLA GP130 2 is a gp130 agonist. Protects against NMDA-induced toxicity in primary hippocampal neurons in vitro. Increases STAT3 phosphorylation in SH-SY5Y cells. Brain penetrant.

化合物库 for UCLA GP130 2

UCLA GP130 2 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for UCLA GP130 2

分子量 270.32
公式 C15H11FN2S
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 339303-87-6
PubChem ID 1284592
InChI Key HXVFUSRCVKYALB-UHFFFAOYSA-N
Smiles FC1=CC=C(C=C1)NC2=NC(C3=CC=CC=C3)=CS2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for UCLA GP130 2

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 27.03 100
ethanol 27.03 100

制备储备液 for UCLA GP130 2

以下数据基于产品分子量 270.32。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.7 mL 18.5 mL 36.99 mL
5 mM 0.74 mL 3.7 mL 7.4 mL
10 mM 0.37 mL 1.85 mL 3.7 mL
50 mM 0.07 mL 0.37 mL 0.74 mL

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参考文献 for UCLA GP130 2

参考文献是支持产品生物活性的出版物。

Alam et al (2018) A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity. ACS Chem.Neurosci. 9 462 PMID: 29161500

If you know of a relevant reference for UCLA GP130 2, please let us know.

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关键词: UCLA GP130 2, UCLA GP130 2 supplier, UCLAGP1302, gp130, agonists, agonism, neuroprotectant, brain, penetrant, interleukin-6, receptor, beta, subunit, signal, transducer, humanin, Cytokines, 6583, Tocris Bioscience

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