主页 / 药理学 / Enzymes / Transferases / Protein Arginine Methyltransferases / Protein Arginine Methyltransferase Inhibitors / UNC 2327

UNC 2327

Cat. No. 5057 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Allosteric inhibitor of PRMT3
化学名： N-1,2,3-Benzothiadiazol-6-yl-N'-[2-oxo-2-(1-piperidinyl)ethyl]urea
纯度： ≥99% (HPLC)
说明书
引用文献
评论
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for UNC 2327

UNC 2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50 = 230 nM). Noncompetitive with both the peptide substrate and cofactor.

化合物库 for UNC 2327

UNC 2327 is also offered as part of the Tocriscreen Epigenetics Library. 了解 Tocris 化合物库的更多信息。

技术数据 for UNC 2327

分子量 319.38
公式 C14H17N5O2S
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 1426152-53-5
PubChem ID 71583615
InChI Key MYTRGTBDVGKKRO-UHFFFAOYSA-N
Smiles O=C(NCC(N3CCCCC3)=O)NC1=CC=C(N=NS2)C2=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for UNC 2327

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 31.94 100

制备储备液 for UNC 2327

以下数据基于产品分子量 319.38。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.13 mL 15.66 mL 31.31 mL
5 mM 0.63 mL 3.13 mL 6.26 mL
10 mM 0.31 mL 1.57 mL 3.13 mL
50 mM 0.06 mL 0.31 mL 0.63 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for UNC 2327

参考文献是支持产品生物活性的出版物。

Liu et al (2013) Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. J.Med.Chem. 56 2110 PMID: 23445220

If you know of a relevant reference for UNC 2327, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Protein Arginine Methyltransferase Inhibitors

关键词: UNC 2327, UNC 2327 supplier, UNC2327, Allosteric, inhibitors, inhibits, protein, arginine, methyltransferases, 3, PRMT3, Protein, Arginine, Methyltransferases, 5057, Tocris Bioscience

篇 UNC 2327 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 UNC 2327 的引用文献。 您是否知道使用了 Tocris UNC 2327 的优秀论文？ 请告知我们.

UNC 2327 的评论

目前没有该产品的评论。 Be the first to review UNC 2327 and earn rewards!

Have you used UNC 2327?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Epigenetics Scientific Review

Epigenetics Scientific Review

Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.