主页 / 药理学 / Enzymes / Proteases / Other Proteases / Other Protease Inhibitors / Y-29794 oxalate

Y-29794 oxalate

Cat. No. 1634 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1634 has been discontinued.

View all Other Proteases products.
说明： Prolyl endopeptidase inhibitor
化学名： [2-[[8-(Dimethylamino)octyl]thio]-6-(1-methylethyl)-3-pyridinyl]-2-thienylmethanone oxalate
纯度： ≥96% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for Y-29794 oxalate

Y-29794 oxalate is a inhibitor of prolyl endopeptidase, a serine peptidase that may be implicated in the biosynthesis of amyloid β-peptide. Potently inhibits rat brain prolyl endopeptidase (Ki = 0.95 nM) in vitro, and prevents amyloid β-peptide deposition in vivo. Orally active and brain penetrant.

技术数据 for Y-29794 oxalate

分子量 508.69
公式 C23H34N2OS2.C2H2O4
储存 Store at -20°C
纯度 ≥96% (HPLC)
CAS Number 146794-84-5
PubChem ID 45073463
InChI Key UUSSHPPSOUAHHP-UHFFFAOYSA-N
Smiles O=C(C2=CC=CS2)C1=CC=C(C(C)C)N=C1SCCCCCCCCN(C)C.O=C(C(=O)O)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Y-29794 oxalate

分析证书/产品说明书
化学品安全技术说明书

参考文献 for Y-29794 oxalate

参考文献是支持产品生物活性的出版物。

Kato et al (1997) Prevention of amyloid-like deposition by a selective prolyl endopeptidase inhibitor, Y-29794, in senescence-accelerated mouse. J.Pharmacol.Exp.Ther. 283 328 PMID: 9336340

Nakajima et al (1992) Y-29794 - a non-peptide prolyl endopeptidase inhibitor that can penetrate into the brain. Neurosci.Lett. 141 156 PMID: 1436628

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Other Protease Inhibitors

关键词: Y-29794 oxalate, Y-29794 oxalate supplier, Prolyl, endopeptidase, inhibitors, inhibits, prolyl, prevents, amyloid, β-peptide, beta-peptide-like, deposition, vivo, Proteases, Proteinases, Beta, Amyloid, Precursor, Protein, APP, Secretase, beta, Peptides, amyloidbeta, amyloidb, Other, 1634, Tocris Bioscience

篇 Y-29794 oxalate 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Y-29794 oxalate 的引用文献。

Y-29794 oxalate 的评论

目前没有该产品的评论。 Be the first to review Y-29794 oxalate and earn rewards!

Have you used Y-29794 oxalate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review