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Submit ReviewRETF-4NA
Description: Selective chymase substrate
Biological Activity for RETF-4NA
RETF-4NA is a chymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form. Displays selectivity over cathepsin G and chymotrypsin.
Technical Data for RETF-4NA
| M. Wt | 713.75 |
| Formula | C32H43N9O10 |
| Sequence |
RETF (Modifications: Arg-1 = N-terminal Ac, Phe-4 = 4-Nitroanilide) |
| Storage | Store at -20°C |
| CAS Number | 1160928-63-1 |
| PubChem ID | 90488886 |
| InChI Key | MGCWUIJMQAZRNY-SJYYQWPBSA-N |
| Smiles | C[C@@H](O)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC1=CC=C(C=C1)[N+]([O-])=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for RETF-4NA
References for RETF-4NA
References are publications that support the biological activity of the product.
Raymond et al (2009) α2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generated activity. J.Immunol. 182 5770 PMID: 19380825
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Keywords: RETF-4NA, RETF-4NA supplier, chymase, substrates, selective, angiotensin, II, enzymes, activators, Other, Proteases, Enzyme, Substrates, /, Activators, Non-selective, AT, Receptors, Angiotensin, 3841, Tocris Bioscience
Citations for RETF-4NA
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