Ligases
Ligases are enzymes which catalyze the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. They belong to the E.C. 6 class of enzymes, which also includes synthases and carboxylases.
Ligase Target Files
Literature for Ligases
Tocris offers the following scientific literature for Ligases to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Programmed Cell Death Poster
There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.
Ligase Gene Data
| Gene | Species | Gene Symbol | Gene Accession No. | Protein Accession No. |
|---|---|---|---|---|
| MDM2 | Human | MDM2 | NM_006880 | Q53XW0 |
| Mouse | Mdm2 | NM_010786 | P23804 | |
| Rat | Mdm2 | NM_001108099 | XP_235169 | |
| DNA Ligase I | Human | LIG1 | NM_000234 | P18858 |
| Mouse | Lig1 | NM_001083188 | P37913 | |
| Rat | Lig1 | NM_030855 | Q9JHY8 | |
| DNA Ligase III | Human | LIG3 | NM_013975 | P49916 |
| Mouse | Lig3 | NM_010716 | P97386 | |
| DNA Ligase IV | Human | LIG4 | NM_002312 | P49917 |
| Mouse | Lig4 | NM_176953 | Q8BTF7 |
Written by Bram van Raam and Guy Salvesen
Our Programmed Cell Death poster gives a summary of the signaling pathways involved in apoptosis, necroptosis and cell survival.
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