Home / Cell Biology / Cell Metabolism / DNA, RNA and Protein Synthesis / AzP3S

AzP3S

Cat. No. 7975 Submit a Review Datasheet / COA / SDS

Discontinued Product

7975 has been discontinued.

View all DNA, RNA and Protein Synthesis products.
Description: Reagent for modifying RNA via 2'-OH sulfonylation; for SHAPE MaP experiments
Chemical Name: 5-((1H-1,2,4-Triazol-1-yl)sulfonyl)-2-(3-(2-(2-azidoethoxy)ethoxy)prop-1-yn-1-yl)pyridine
Purity: ≥95% (HPLC)
Datasheet
Citations
Reviews
Literature (2)
Biological Activity Technical Data Datasheets References

Biological Activity for AzP3S

AzP3S is a pyridine sulfonyl triazole for modifying RNA via RNA 2'-OH sulfonylation. AzP3S can be used for RNA SHAPE-MaP experiments in cell lines and bacteria. Allows fluorescent labeling of RNA using Cu-free click chemistry. Stable in aqueous media and in storage at room temperature, can be purified with silica gel chromatography.

Technical Data for AzP3S

M. Wt 377.38
Formula C14H15N7O4S
Storage Store at -20°C
Purity ≥95% (HPLC)
InChI Key YXXBRUUKGYGVKP-UHFFFAOYSA-N
Smiles O=S(C1=CC=C(N=C1)C#CCOCCOCCN=[N+]=[N-])(N2C=NC=N2)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for AzP3S

References are publications that support the biological activity of the product.

Chatterjee et al (2023) Sulfonylation of RNA 2'-OH groups. ACS Cent.Sci 9 531 PMID: 36968531

View Related Products by Target

Keywords: AzP3S, AzP3S supplier, pyridine, sulfonyl, triazaole, RNA, SHAPE, MAP, Copper, cu, free, click, chemistry, DNA,, and, Protein, Synthesis, 7975, Tocris Bioscience

Citations for AzP3S

Citations are publications that use Tocris products.

Currently there are no citations for AzP3S.

Reviews for AzP3S

There are currently no reviews for this product. Be the first to review AzP3S and earn rewards!

Have you used AzP3S?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cell Cycle and DNA Damage Research Product Guide

Cell Cycle and DNA Damage Research Product Guide

This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:

  • Cell Cycle and Mitosis
  • DNA Damage Repair
  • Targeted Protein Degradation
  • Ubiquitin Proteasome Pathway
  • Chemotherapy Targets
Huntington's Disease Research Product Guide

Huntington's Disease Research Product Guide

This product guide provides a background to Huntington's disease research and lists around 100 products for the study of:

  • Somatic Instability
  • Proteolysis and Inclusion Bodies
  • Transcriptional Dysregulation
  • Mitochondrial Dysfunction
  • Nuclear-Cytoplasmic Transport Interference
  • Excitotoxicity
  • Stem Cells