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Submit ReviewBRD 9876
Description: ATP non-competitive kinesin Eg5 inhibitor
Chemical Name: 6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile
Purity: ≥99% (HPLC)
Biological Activity for BRD 9876
ATP non-competitive kinesin Eg5 inhibitor. Selectively inhibits microtubule-bound Eg5. Inhibits multiple myeloma cell growth (IC50 = 2.2 μM).
Technical Data for BRD 9876
| M. Wt | 234.3 |
| Formula | C16H14N2 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 32703-82-5 |
| PubChem ID | 613000 |
| InChI Key | MKILROQBJOOZKC-UHFFFAOYSA-N |
| Smiles | CC(C)(C)C2=CC1=CC(C#N)=C(C#N)C=C1C=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for BRD 9876
References for BRD 9876
References are publications that support the biological activity of the product.
Chattopadhyay et al (2015) Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitors. Cell Rep. 10 755 PMID: 25660025
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Keywords: BRD 9876, BRD 9876 supplier, BRD9876, ATP, non-competitive, kinesin-5, Eg5, inhibitors, inhibits, microtubule-bound, Kinesin, Mitosis, 5454, Tocris Bioscience
Citations for BRD 9876
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Cell Cycle and DNA Damage Research Product Guide
This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:
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