Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewMyelin Basic Protein (87-99)
Description: Major antigenic component implicated in the pathophysiology of multiple sclerosis
Purity: ≥95% (HPLC)
Biological Activity for Myelin Basic Protein (87-99)
Myelin Basic Protein (87-99) is an encephalitogenic peptide that induces T cell proliferation with Th1 polarization in the CNS. Major antigenic component implicated in the pathophysiology of multiple sclerosis.
Technical Data for Myelin Basic Protein (87-99)
| M. Wt | 1555.8 |
| Formula | C74H114N20O17 |
| Sequence | VHFFKNIVTPRTP |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 118506-26-6 |
| PubChem ID | 25077562 |
| InChI Key | XSSZRUKIAIQNAZ-SAKFXWCOSA-N |
| Smiles | [H]N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Myelin Basic Protein (87-99)
References for Myelin Basic Protein (87-99)
References are publications that support the biological activity of the product.
Jones et al (1992) The synthetic 87-99 peptide of myelin basic protein is encelphalitogenic in Buffalo rats. J.Neuroimmunol. 37 203 PMID: 1373154
Deraos et al (2008) Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP87-99) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: Implications in triggering disease. J.Med.Chem. 51 7834 PMID: 19053745
Hofstetter et al (2005) Does the frequency and avidity spectrum of the neuroantigen-specific T cells in the blood mirror the autoimmune process in the central nervous system of mice undergoing experimental allergic encephalomyelitis? J.Immunol. 22 4598
View Related Products by Target
Keywords: Myelin Basic Protein (87-99), Myelin Basic Protein (87-99) supplier, antigenic, component, implicated, pathophysiology, multiple, sclerosis, Encephalitogenic, peptide, Neuronal, Metabolism, Miscellaneous, Compounds, 3399, Tocris Bioscience
Citations for Myelin Basic Protein (87-99)
Citations are publications that use Tocris products.
Currently there are no citations for Myelin Basic Protein (87-99).
Reviews for Myelin Basic Protein (87-99)
There are currently no reviews for this product. Be the first to review Myelin Basic Protein (87-99) and earn rewards!
Have you used Myelin Basic Protein (87-99)?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image