Phospho-Glycogen Synthase Peptide-2 (substrate)

Discontinued Product

1352 has been discontinued.

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Description: Glycogen synthase kinase-3 substrate (synthetic)
Alternative Names: GS peptide-2
Datasheet
Citations (1)
Reviews

Biological Activity

Phospho-Glycogen Synthase Peptide-2 (substrate) is a synthetic peptide suitable as a substrate for glycogen synthase kinase-3 (GSK-3).

Technical Data

M. Wt 3029
Formula C123H191N40O48P
Sequence YRRAAVPPSPSLSRHSSPHQSEDEEE

(Modifications: Ser-21 = OPO3H2)

Storage Desiccate at -20°C
CAS Number 851366-97-7
PubChem ID 90479786
InChI Key IIMKCITWGMPAKU-LKAJVXBKSA-N
Smiles [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](COP(O)(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Sutherland et al (1993) Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in Ins and growth factor signalling. Biochem.J. 296 15 PMID: 8250835

Woodgett (1989) Use of peptide substrates for affinity purification of protein-serine kinases. Anal.Biochem. 180 237 PMID: 2554753

Keywords: Phospho-Glycogen Synthase Peptide-2 (substrate), Phospho-Glycogen Synthase Peptide-2 (substrate) supplier, GSK-3, synthetic, Glycogen, synthase, kinase-3, kinases, Carbohydrate, Metabolism, Enzyme, Substrates, Activators, GSpeptide2, GS, peptide-2, /, Synthase, Kinase, 3, 1352, Tocris Bioscience

1 Citation for Phospho-Glycogen Synthase Peptide-2 (substrate)

Citations are publications that use Tocris products. Selected citations for Phospho-Glycogen Synthase Peptide-2 (substrate) include:

Stoothoff et al (2005) FRAT-2 preferentially increases glycogen synthase kinase 3 β-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylation. PLoS One 280 270 PMID: 15522877


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