Home / Pharmacology / Enzymes / Kinases / Protein Kinase C / Protein Kinase C Inhibitors / PKC (19-36)

PKC (19-36)

Cat. No. 4058 1 Citation Submit a Review Datasheet / COA / SDS

Discontinued Product

4058 has been discontinued.

View all Protein Kinase C products.
Description: Pseudosubstrate peptide; inhibitor of PKC
Datasheet
Citations (1)
Reviews
Biological Activity Technical Data Datasheets References

Biological Activity for PKC (19-36)

Pseudosubstrate peptide inhibitor of protein kinase C (IC50 = 0.18 μM). Attenuates vascular hyperproliferation and hypertrophy induced by high glucose. Inhibits DNA and protein synthesis in vascular smooth muscle cells (VSMCs) in a dose-dependent manner.

Negative Control also available.

Technical Data for PKC (19-36)

M. Wt 2151.48
Formula C93H159N35O24
Sequence RFARKGALRQKNVHEVKN
Storage Store at -20°C
CAS Number 113731-96-7
PubChem ID 71308428
InChI Key NHCJMYZDRROLEW-OFXZVSIYSA-N
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for PKC (19-36)

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet

References for PKC (19-36)

References are publications that support the biological activity of the product.

Yasunari et al (1996) Possible involvement of phospholipase D and protein kinase C in vascular growth induced by elevated glucose concentration Hypertension 28 159 PMID: 8707376

View Related Products by Target

View Related Products by Product Action

View all Protein Kinase C Inhibitors

Keywords: PKC (19-36), PKC (19-36) supplier, PKC, inhibitors, inhibits, pseudosubstrate, protein, kinase, C, fragment, (19-36), PKCI, Protein, Kinase, 4058, Tocris Bioscience

1 Citation for PKC (19-36)

Citations are publications that use Tocris products. Selected citations for PKC (19-36) include:

Glovaci and Chapman (2015) Activation of Phosphatidylinositol-Linked DA Receptors Induces a Facilitation of Glutamate-Mediated Synaptic Transmission in the Lateral Entorhinal Cortex. Mol Med Rep 10 e0131948 PMID: 26133167

Reviews for PKC (19-36)

There are currently no reviews for this product. Be the first to review PKC (19-36) and earn rewards!

Have you used PKC (19-36)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review