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Submit ReviewSCOTfluor 510, fluoro
Description: Amine-reactive fluorescent probe precursor
Chemical Name: 4-Fluoro-7-nitro-2,1,3-benzoselenadiazole
Purity: ≥90% (HPLC)
Biological Activity for SCOTfluor 510, fluoro
SCOTfluor 510, fluoro is a precursor that, upon reaction with amine groups, can be used for the synthesis of fluorescent probes. Can be used to generate functionalized lactic acid, glucose and ceramide fluorescent probes for real-time, in situ imaging of small molecule metabolites in vivo and in live cells. Fluorescent adduct excitation maximum = 510 nm; emission maximum = 606 nm.
Licensing Information
Sold under license from the University of Edinburgh
Usage Guidelines for SCOTfluor 510, fluoro
This product is provided for use in onward chemistry. Suitable solvents can be used.
Optical Data for SCOTfluor 510, fluoro
| Emission Color | Orange |
|---|---|
| λabs | 510 nm |
| λem | 606 nm |
| Extinction Coefficient (ε) | 16300 M-1cm-1 |
| Quantum Yield (φ) | 0.2 |
| Closest Laser line | 488 nm |
| Reactivity | Primary amines |
| Cell Permeable | Yes |
| Application | Conjugation to Primary Amines, in vivo Imaging |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectral Viewer
Technical Data for SCOTfluor 510, fluoro
| M. Wt | 246.06 |
| Formula | C6H2FN3O2Se |
| Storage | Store at -20°C |
| Purity | ≥90% (HPLC) |
| CAS Number | 2351940-09-3 |
| PubChem ID | 155694544 |
| InChI Key | XRHUSGRDOGVFEO-UHFFFAOYSA-N |
| Smiles | FC1=CC=C(N(=O)=O)C2=N[Se]N=C12 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for SCOTfluor 510, fluoro
References for SCOTfluor 510, fluoro
References are publications that support the biological activity of the product.
Benson et al (2019) SCOTfluors: small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism. Angew.Chem.Int.Ed.Engl. 58 6911 PMID: 30924239
If you know of a relevant reference for SCOTfluor 510, fluoro, please let us know.
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Fluorescent Dyes and Probes Research Product Guide
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